Malvern Panalytical – Chromatography & Mass Spectrometry – OMNISEC

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  • OMNISEC brochure

The world’s most advanced multi-detector GPC / SEC system

Malvern’s OMNISEC is a Gel Permeation Chromatography (GPC) / Size Exclusion Chromatography (SEC) system for the measurement of absolute molecular weight, molecular size, intrinsic viscosity, branching and other parameters. It includes OMNISEC RESOLVE, the integrated GPC/SEC module, OMNISEC REVEAL, the integrated multi-detector module and OMNISEC software for the characterization of synthetic and natural polymers, and proteins.

DKSH is the exclusive distributor in Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Taiwan, Thailand and Vietnam.

Technical Specifications

Control strength, toughness, durability, brittleness, processability and branchingPolystyrene, nylon, PET, PVC, polyester, nitrocellulose, resins, epoxys, polyurethanes, PVA
Measure degradation and drug delivery ratesPLA, PLGA, PEG, polycaprolocatone
Grade natural polymers and polysaccharidesAlginates, xanthans, Gum Arabic, starch derivatives (e.g. maltodextrin), cellulose derivatives (e.g. HEC), carageenan, gelatin, guar gum, chitosan, hyaluronic acid
Control formulation viscosityAlkyds, acrylics, polyurethanes, polyesters, resins, epoxys, PVA
Control food mouth-feel and gellingPectins, alginates, xanthans, Gum Arabic, guar gum, starch derivatives (e.g. maltodextrin), carageenans
Assess and predict activity by measuring molecular weightProteins, antibodies, mAbs
Predict and understand immunogenicity and efficacyAggregates of proteins, biopharmaceuticals, biologics and mAbs
Control half-life, cell permeability and understand crystallization of protein conjugatesPEGylated proteins, membrane proteins, antibody-drug-conjugates
Pump flow rate0.005 – 10 mL/min
Pressure range0 – 5000 PSI (34.5 MPa)
Sample container typesHPLC vials or 96-well microtiter plates
Injection volume1 – 300 µL
Syringe volume250 µL standard

Key Features

  • Molecules are separated by their hydrodynamic radius
  • Better intrinsic viscosity measurements thanks to automated balancing
  • Reduced service cost and time thanks to user-exchangeable capillaries
  • Measure as little as 100 ng of material and molecular weights down to 200 Da

OMNISEC: Sensitive and Accurate Characterization of Polymers & Proteins

Malvern’s OMNISEC is a complete gel permeation/size exclusion chromatography (GPC/SEC) solution for the advanced characterization of synthetic and natural polymers, and proteins. This integrated GPC/SEC platform is made up of 3 components – OMNISEC RESOLVE, an integrated pump, degasser, autosampler and column oven; OMNISEC REVEAL, an integrated multi-detector; and OMNISEC software. This video describes the main features of OMNISEC and the benefits they bring to customers seeking the highest level of sensitivity and accuracy in their measurements of macromolecules.

Key Industries

  • Biopharmaceutical and Biotechnology
  • Chemical
  • Medical
  • Pharmaceutical
  • Polymers, Plastics and Rubbers
  • Optical

Brand

Malvern Panalytical

Malvern Panalytical was formed by the merger of Malvern Instruments Limited and PANalytical B.V. on 1st January 2017, has headquarters in both Almelo (the Netherlands), and in Malvern (UK), and employs over 2,000 people worldwide. The combined entity is a strong player and innovator in the materials characterization market and will leverage the strengths of the individual companies in their end markets, ranging from building materials to pharmaceuticals and from metals and mining to nanomaterials.

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